Centum is listed on the Nairobi Securities Exchange and cross-listed on the Uganda Securities Exchange. It has interests in private equity, quoted equity and real estate investments in East Africa as well as investments in listed securities across Sub-saharan Africa. Centum makes investments in both public and private sectors, with an extensive investment portfolio consisting of over 20 investee companies, consisting of wholly and partly owned subsidiaries, associate companies and unquoted companies. The quoted equity segment acquires influential or controlling equity stakes in quoted companies within Sub-Saharan Africa. 

Centum has eight distinct business lines namely; Real estate & infrastructure, financial services, fast moving consumer goods, power, education, ICT, agribusiness and health.

The company's real estate and infrastructure subsidiary, Athena Properties Limited, is engaged in developing real estate solutions, including retail, entertainment, offices, hotel and serviced apartments. The real estate projects include Two Rivers project in Nairobi, and Pearl Marina project in Uganda.

The company through several subsidiaries, is engaged in manufacturing, distilling, importing and distributing of both alcoholic and non-alcoholic beverages. These subsidiaries include Rasimu Limited, Centum BVI Limited, eTransact Limited, Centum Exotics Limited, Almasi Beverages Limited.

Centum financial services interests include Nabo Capital Limited, a wholly owned asset management subsidiary and recently, acquisition of a 65% controlling stake in K-Rep Bank for KES 2.3B, later renamed Sidian Bank. Centum is the first NSE listed company in Kenya to have a bank as a subsidiary.